The Simulator

The VHIS simulator is the main and more important deliverable of the project. It is available at the simulator web site (www.immunogrid.eu).

Since the simulator has been designed for computationally intensive jobs, the access to the simulator is restricted. The access is granted through partnering with one of the principal contributors.

Other results

Several other tools and components were developed and are now available for use or further development. A complete description is contained in this document (extracted from D9.7).

Here you can find a summary list:

conceptual models and ontologies

Immune Ontology
Data model: Formal definition of molecules and interactions
imgt.cines.fr (IMGT)
Documents    (ImmunoGrid)

3D structures capability
Repository: Data sets of antigenic structures with epitope mapping
www.immunogrid.eu 

ImmunoTome/ImmunoMiner
Tool/corpus: Immunological data mining
immunominer.cryst.bbk.ac.uk  (Birkbeck)

molecular-level models

HLA prediction models class I
Algorithm: Molecular-level models of immune interactions www.cbs.dtu.dk  (DTU)

HLA prediction models class II
Algorithm: Molecular-level models of immune interactions
www.cbs.dtu.dk  (DTU)

system-level models

model for cancer immuno-prevention
Algorithm: Based on SimTriple, a system-level models of cancer vaccination
www.immunomics.eu  (UniCT)

model for the optimal schedule of cancer vaccine
Algorithm: Based on Simprot, a genetic algorithm based tool to optimize vaccine schedule
www.immunomics.eu  (UniCT)

model for atherosclerosis
Algorithm: Based on SimTriplex
www.immunomics.eu  (UniCT)

model for Influenza A
Algorithm: Based on SimTriplex
www.immunomics.eu  (UniCT)

model for HIV
Algorithm: Based on C-IMMSIM
www.iac.cnr.it/~filippo/  (CNR)

model for EBV
Algorithm: Based on C-IMMSIM For the simulation of Epstein-Barr (EBV) infection
www.iac.cnr.it/~filippo/  (CNR)

General model for other pathologies
Algorithm: System-level models of immune system related pathologies
www.immunomics.eu   (UniCT)
www.iac.cnr.it/~filippo/  (CNR)

databases and
other tools

Influenza A antigen database
Database: Up-to-date set of Influenza A antigens and potential targets
www.immunogrid.eu  (ImmunoGrid)

Other pathologies antigen databases
Database: Up-to-date set of other pathologies antigens and potential targets
www.immunogrid.eu  (ImmunoGrid)

Grid framework and Applications
Technology: An High Throughput environment for running simulations of the immune system
www.cryst.bbk.ac.uk/  (Birkbeck)
e.rossi@cineca.it  (CINECA)

Mice tissue Biobank
Biobank: Tissue repositories from mice used in immuno-prevention experiments
www.lollini.it  (UniBO)

Educational simulators
Web resource: Selected examples of ImmunoGrid projects
www.immunogrid.eu  (ImmunoGrid)