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The project
The ImmunoGrid is an implementation of the virtual human immune system using grid technologies.
It will be able to simulate immune processes at natural scale and provides tools for applications in clinical immunology and the design of vaccines and immunotherapies.
The developed set of tools will be validated with experimental data and used in clinical applications for development of immunotherapies in cancer and chronic infections.
Computational models are required because immune system is complex and has combinatorial nature, experimental approaches are expensive, and there are restrictions on the experimentation that can be performed in humans.
The target user groups are:
- clinicians
- developers of the vaccines and immunotherapies.
The unique aspect of this proposal is that it aims at connecting molecular level interactions (which regulate immune responses) with system level models (which study behaviour of the immune system as a whole).
This is a novel approach to disease prevention and treatment which will help improve human health.
Applications of the ImmunoGrid include
- modelling of the natural-size complex system on a large scale.
- the implementation of individual immune system models across the grid nodes
The first pubblic Deliverable of the project is on-line